How Smell Works

Smell is our first response to dangers like fire and gas leaks. See more human senses pictures.
Smell is our first response to dangers like fire and gas leaks. See more human senses pictures
© Photographer: Christian Bernfeld | Agency:Dreamstime

Smell is often our first response to stimuli. It alerts us tofirebefore we see flames. It makes us recoil before we taste rottenfood。虽然闻起来是一个基本的意义上说,它也是一个t the forefront of neurological research. Scientists are still exploring how, precisely, we pick up odorants, process them and interpret them as smells. Why are researchers, perfumers, developers and even government agencies so curious about smell? What makes a seemingly rudimentary sense so tantalizing?

Smell, liketaste, is a chemical sense detected by sensory cells calledchemoreceptors。When an odorant stimulates the chemoreceptors in the nose that detect smell, they pass onelectricalimpulses to thebrain。The brain then interprets patterns in electrical activity as specific odors and olfactory sensation becomes perception -- something we can recognize as smell. The only other chemical system that can quickly identify, make sense of and memorize new molecules is theimmune system

Advertisement

But smell, more so than any other sense, is also intimately linked to the parts of the brain that process emotion and associative learning. The olfactory bulb in the brain, which sorts sensation into perception, is part of thelimbic system-- a system that includes the amygdala and hippocampus, structures vital to our behavior, mood andmemory。This link to brain's emotional center makes smell a fascinating frontier in neuroscience, behavioral science andadvertising

In this article, we'll explore how humans perceive smell, how it triggers memory and the interesting (and sometimes unusual) ways to manipulate odor and olfactory perception.

Advertisement

Detection of Odorants

Durian is popular in Southeast Asia. Some people love the spiky fruit's pungent odor, and others think it's revolting.
Durian is popular in Southeast Asia. Some people love the spiky fruit's pungent odor, and others think it's revolting.
© Photographer: Kuan Chong Ng | Agency:Dreamstime

Smell begins when airborne molecules stimulate olfactory receptorcells。If a substance is somewhat volatile (that is, if it easily turns into a gas), it will give off molecules, or odorants. Nonvolatile materials likesteeldo not have a smell.

Temperature and humidity affect odor because they increase molecular volatility. This is why trash smells stronger in the heat andcarssmell musty after rain. A substance's solubility also affects its odor. Chemicals that dissolve inwaterorfatare usually intense odorants.

Advertisement

When an air current sweeps an odorant up through the nostrils, the molecules hit theolfactory epithelium-- the center of olfactory sensation. The epithelium occupies only about one square inch of the superior portion of the nasal cavity. Mucus secreted by the olfactory gland coats the epithelium's surface and helps dissolve odorants.

Olfactory receptor cellsare neurons with knob-shaped tips calleddendrites。Olfactory hairs that bind with odorants cover the dendrites. When an odorant stimulates a receptor cell, the cell sends an electrical impulse to theolfactory bulbthrough theaxonat its base.

Supporting cellsprovide structure to the olfactory epithelium and help insulate receptor cells. They also nourish the receptors and detoxify chemicals on the epithelium's surface.Basal stem cellscreate new olfactory receptors through cell division. Receptors regenerate monthly -- which is surprising because mature neurons usually aren't replaced.

While receptor cells respond to olfactory stimuli and result in the perception of smell,trigeminal nerve fibersin the olfactory epithelium respond topain。When you smell something caustic like ammonia, receptor cells pick up odorants while trigeminalnervefibers account for the sharp sting that makes you immediately recoil.

But how does odor actually become smell? In the next section, we'll learn more about olfactory receptors and odorant patterns.

Advertisement

Olfactory System

Richard Axel (left) and Linda Buck won a Nobel Prize for their work on smell.
Richard Axel (left) and Linda Buck won a Nobel Prize for their work on smell.
Henrik Montgomery/AFP/Getty Images

How does thebrain认识、分类和记住的巨大variety of odors? In 1991, Richard Axel and Linda Buck published a groundbreaking paper that shed light on olfactory receptors and how the brain interprets smell. They won the 2004Nobel Prizein Physiology or Medicine for the paper and their independent research.

Axel and Buck discovered a largegenefamily -- 1,000 genes, or 3 percent of the human total -- that coded for olfactory receptor types. They found that every olfactory receptor cell has only one type of receptor. Each receptor type can detect a small number of related molecules and responds to some with greater intensity than others. Essentially, the researchers discovered that receptor cells are extremely specialized to particular odors.

Advertisement

Axel and Buck also found that each olfactory receptor type sends its electrical impulse to a particular microregion of the olfactory bulb. The microregion, orglomerulus, that receives the information then passes it on to other parts of the brain. The brain interprets the "odorant patterns" produced by activity in the different glomeruli as smell. There are 2,000 glomeruli in the olfactory bulb -- twice as many microregions as receptor cells -- allowing us to perceive a multitude of smells.

An illustration of how receptors function in the olfactory system
An illustration of how receptors function in the olfactory system
Image courtesyNobelprize.org

Another researcher, however, has challenged the idea that humans have a large number of receptor types that respond only to a limited number of molecules. Biophysicist Luca Turin developed the quantum vibration theory in 1996 and suggests that olfactory receptors actually sense the quantum vibrations of odorants'atoms。While molecular shape still comes into play, Turin purports that the vibrational frequency of odorants plays a more significant role. He estimates that humans could perceive an almost infinite number of odors with only about 10 receptors tuned to different frequencies.

Next, we'll learn about how smells trigger memory and find out how much cognition actually influences perception.

Advertisement

Smell and Memory

We make most of our olfactory memories as children.
We make most of our olfactory memories as children.
William Thomas Cain/Getty Images

A smell can bring on a flood of memories, influence people's moods and even affect their work performance. Because the olfactory bulb is part of the brain'slimbic system, an area so closely associated with memory and feeling it's sometimes called the "emotional brain," smell can call up memories and powerful responses almost instantaneously.

The olfactory bulb has intimate access to theamygdala, which processes emotion, and thehippocampus, which is responsible for associative learning. Despite the tight wiring, however, smells would not trigger memories if it weren't forconditioned responses。When you first smell a new scent, you link it to an event, a person, a thing or even a moment. Your brain forges a link between the smell and a memory -- associating the smell ofchlorinewith summers at thepoolor lilies with a funeral. When you encounter the smell again, the link is already there, ready to elicit a memory or a mood. Chlorine might call up a specific pool-related memory or simply make you feel content. Lilies might agitate you without your knowing why. This is part of the reason why not everyone likes the same smells.

Advertisement

Because we encounter most new odors in our youth, smells often call up childhood memories. But we actually begin making associations between smell and emotion before we're even born. Infants who were exposed toalcohol, cigarette smoke orgarlicin the womb show a preference for the smells. To them, the smells that might upset other babies seem normal or even comforting.

在下一节中,我们将看看一些名人18新利最新登入e use smell's ability to trigger memory.

Advertisement

Scent Marketing

The California Milk Processor Board launched a scent marketing scheme in 2006 to accompany its "Got Milk?" campaign. The city of San Francisco called for an immediate removal of the cookie-scented strips after complaints.
The California Milk Processor Board launched a scent marketing scheme in 2006 to accompany its "Got Milk?" campaign. The city of San Francisco called for an immediate removal of the cookie-scented strips after complaints.
贾斯汀Sullivan/Getty Images

Advertisers are eager to cash in on the close link between smell, memory and mood. Real estate agents have long usedscent marketingas a way of putting clients at ease. Sellers set fresh pie or cookies on countertops to make a house seem comfy and livable. But because there's a limit to how many pies one agent can bake, companies that sell aroma-marketing systems are stepping up. Housing developments, hotels, stores and evencarmanufacturers are turning to customized scents to help set a mood and maybe even make an impression.

Scent marketing is the latest trick to stand out from the visual and auditory barrage that dominates advertising. These scents, however, are a far cry from the strong smells of incense and patchouli at the bead store. They're subtle and almost imperceptible to the unwitting sniffer. Developers use carefully tuned scents to lure customers into a sense of well-being. Stores that sell shoes or shirts, items ideally not associated with odor, formulate aromas of ivy or crisp linen. Some companies even strive to develop a "brand scent," something that customers will associate with the company as much as a logo.

Advertisement

To learn more about smell and the other senses, sniff out the links on the next page.

Lots More Information

Related HowStuffWorks Links

More Great Links

  • Anosmia Foundation. http://www.anosmiafoundation.org/index.shtml
  • Gordon, Rachel. "Freshly baked ads are toast." San Francisco Chronicle. December 5, 2006. http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2006/12/05/BAGQDMPQB319.DTL
  • Herz, Rachel S. "Do scents affect people's moods or work performance?" Scientific American. November 11, 2002. http://www.sciam.com/askexpert_question.cfm?articleID=00034AFF-91FE-1DC9-AF71809EC588EEDF&sc=I100322
  • Miller, Tom. “A MATTER OF TASTE; I Was a Middle-Aged Anosmic.” The New York Times. September 22, 2003. http://query.nytimes.com/gst/fullpage.html?res=9C07EFD8133AF931A1575AC0A9659C8B63&sec=&spon=&pagewanted=1
  • Minkel, J.R. "Is Sense of Smell Powered by Quantum Vibrations?" Scientific American. December 12, 2006. http://www.sciam.com/article.cfm?articleID=885622AA-E7F2-99DF-3859D89E5980A4B2&sc=I100322
  • Mossman, Kaspar. "Ooh, That Smell." Scientific American. September 21, 2005. http://www.sciam.com/article.cfm?articleID=00067444-568B-132F-949983414B7F0000&sc=I100322
  • "Our Nobel Laureates." Fred Hutchinson Cancer Research Center. http://www.fhcrc.org/research/nobel/buck/
  • "Press Release." Nobelprize.org. October 4, 2004. http://nobelprize.org/nobel_prizes/medicine/laureates/2004/press.html
  • Rockel, Anthony. "The Nose Knows." Medical Post. May 2, 2006. http://proquest.umi.com/pqdweb?did=1036304501&Fmt=3&clientId=30451&RQT=309&VName=PQD
  • "Secrets of smell land Nobel Prize." BBC News. October 4, 2004. http://news.bbc.co.uk/2/hi/health/3713134.stm
  • "Sense of smell 'underestimated.'" BBC News. December 18, 2006. http://news.bbc.co.uk/2/hi/health/6183379.stm
  • "Sensory Reception, human." Encyclopaedia Britannica Online. http://search.eb.com/eb/article-64853
  • Shepherd, Gordon M. "Outline of a Theory of Olfactory Processing and its Relevance to Humans." http://chemse.oxfordjournals.org/cgi/reprint/30/suppl_1/i3.pdf
  • Slotnick, Rebecca Sloan. "Science that Stinks." American Scientist. May-June, 2002.
  • http://www.americanscientist.org/template/AssetDetail/assetid/14758
  • Steinberger, Mike. "Do You Taste What I Taste?" Slate. June 20, 2007. http://www.slate.com/id/2168762
  • Steinberger, Mike. "Am I a Supertaster?" Slate. June 21, 2007. http://www.slate.com/id/2168768/
  • Steinberger, Mike. "Do You Want To Be a Supertaster?" June 22, 2007. http://www.slate.com/id/2168868/
  • Vitez, Michael. "The Nose Knows." Philadelphia Inquirer. August 16, 2001. http://wf2la2.webfeat.org/
  • Vlahos, James. "Scent and Sensibility." The New York Times. September 9, 2007. http://www.nytimes.com/2007/09/09/realestate/keymagazine/909SCENT-txt.html?pagewanted=1&n=Top/News/U.S./U.S.%20States,%20Territories%20and%20Possessions/Nevada&_r=1
Featured

Advertisement

Loading...
Baidu